Electric Double Layer Simulation on Transient State for Sensitivity Enhancement of Affinity-Based Biosensor

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We have presented a numerical simulation for the affinity-based electrical biosensor system on the steady and transient state. Considering the screening length in the solutions, the solution with low ion concentration can be better measurement condition to get the high sensitivity. The transient electro-diffusion ionic flow caused by step-pulse input bias leads to the enhancement of the sensitivity. From these results, we can find a new sensing measurement scheme to achieve high sensitivity in the biosensor applications.

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Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational (Volume 2)
Published: June 18, 2012
Pages: 586 - 589
Industry sectors: Advanced Materials & Manufacturing | Sensors, MEMS, Electronics
Topic: Informatics, Modeling & Simulation
ISBN: 978-1-4665-6275-2