Kidwell D.A., Wei E., Lanese J.N., Mulvaney S.
Naval Research Laboratory, US
Keywords: catalytic label, increased sensitivity, lateral-flow immunoassays
Lateral-flow immunoassays (LFIAs) are a widely used point- of-care technology. They are most familiar as home-pregnancy tests, but are also employed for testing for a wide variety of diseases, biomarkers, and even small molecules. By substituting catalytic particles for the conventional colorimetric labels, we have demonstrated an increase in sensitivity of at least 1000x without placing an undue burden on the user.
Journal: TechConnect Briefs
Volume: TechConnect Briefs 2019
Published: June 17, 2019
Pages: 427 - 430
Industry sector: Medical & Biotech
Topics: Biomaterials, Diagnostics & Bioimaging
ISBN: 978-0-9988782-8-7