transdermal – TechConnect Briefs

An ex-vivo and in-vivo performance of a switchable carbon nanotube membrane device for transdermal nicotine delivery

Gulati G.K., Berger L., Jackson Hinds B., University of Washington, US

Purpose: Transdermal nicotine patches and nicotine gums therapy along with psychological counseling support is most widely used therapy for smoking cessation, but has low success rate of 25% for 2 year without relapse. An ideal [...]

Polymersome macromolecule delivery across intact human skin

Pegoraro C., MacNeil S., Battaglia G., University of Sheffield, UK

Skin is a highly stratified and impermeable tissue that confers specific size, charge, hydrophilic and lipophilic constraints on the types of molecules that can diffuse across it. Here we report the use of a novel [...]

Nanoparticulate systems of Acyclovir for Topical use in Herpes treatment –formulation, characterization and evaluation

Srinivas P., Devaraj R., Sri Venkateshwara College of Pharmacy, IN

Of the numerous drugs that are available for systemic treatment of HSV infection, a cream containing an antiviral agent is still the most convenient method of treating herpes simplex labialis/facialis in the general population. Acyclovir [...]