Preparation of Novel Ferrocene-based Shell Cross-linked Thermoresponsive Hybrid Micelles with Anti-tumor Efficacy

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Shell cross-linked (SCL) thermoresponsive hybrid micelle consisting of a cross-linked thermoresponsive hybrid shell and a hydrophobic core domain was synthesized from poly(N-isopropylacrylamide-co-aminoethyl methacrylate)-b-polymethyl methacrylate (P(NIPAAm-co-AMA)-b-PMMA) amphiphilic block copolymers via a two-step process: micellization of P(NIPAAm-co-AMA)-b-PMMA [...]