Toxicity and Pharmacokinetics of uPAR-targeted Human ATF-conjugated Iron Oxide Nanoparticles Following Systemic Delivery in Rhesus Monkey
Increasing evidence support the potential of a novel cell surface receptor-targeted MRI nanoprobe produced by conjugating a recombinant peptide amino-terminal fragment (ATF) of urokinase plasminogen activator (uPA) to magnetic iron oxide nanoparticles (IONP) in targeted [...]