Poisson-Nernst-Planck – TechConnect Briefs

Spatial profiles of electrical conductivity, fluid admittance and water flow in a charged nanopore

Virdi G., Glavinovic M.I., McGill University, CA

The transport of charged particles and water through nanofluidic pores is governed by the concentration, potential and pressure gradients. Better understanding of the interplay of these forces, of the resulting fluxes of charged particles and [...]

Ion Channel Simulations by the TR-PNP Model and the Excess Chemical Potential Approach

Hu S., Hess K., Beckman Institute, University of Illinois at Urbana-Champaign, US

We describe a new method referred to as TR-PNP model to study general types of nanostructure ion channels. Our method extends the common continuum methods to include particle like properties, such as the ion trapping [...]

Structure-function study of Porins

Chen D.P., Tang J., Eisenberg R.S., Rush Medical College, US

Single channel current-voltage (IV) relations were measured from proteins that form channels across the outer membranes of Gram-negative bacteria-porins and their mutants in solutions of KCl. The wild-type porins and some of their specific mutants [...]

Three-Dimensional Continuum Simulation of Biological Ion Channels

van der Straaten T.A., Tang J., Eisenberg R.S., Ravaioli U., Aluru N., Rush Medical College, US

We present a self-consistent continuum 3-D simulation of ion permeation through the ompF porin channel, a protein found in the membrane of the e-coli bacterium. The model is based on the simultaneous solution of Poisson's [...]