peptides – TechConnect Briefs

Hybrid Programmable Peptide Crosslinkers as Enzyme-Regulated Drug Delivery Vehicles

Rouge J.L., University of Connecticut, US

Biology has evolved the quintessential nucleic acid delivery vehicle, the virus, using proteins built from self-assembled peptide subunits. These viral protein coats are then degraded by specific enzymes, depending on their location, releasing their contents [...]

Uses of Self-assembled Peptide structures doped with electroluminescent compounds

Martins T.D., Ribeiro A.C.C., Souza G.A., Camargo H.S., Cordeiro D.S., Federal University of Goias, BR

Several distinct technological applications can be addressed to self-assembled peptide nanostructures, especially when electroluminescent organic compounds are inserted in these structures. Depending on the preparation methods, these additives can drive the peptide´s self-assembling, resulting in [...]

A Specific Surface-coating Peptide for Rare Earth Nanomaterials

Zhang Y.J., Zhou W., Wen L.P., University of Science and Technology of China, CN

The induction of autophagy on exposure of cells to a variety of nanoparticles represents both a safety concern and an application niche for engineered nanomaterials. Using phage display, we have discovered an 11-amino acid peptide [...]

Peptide Nanoparticle Catalysis

Heller M.J., Cheung M., Takahashi T., University of California San Diego, US

Improved catalysis for more efficient chemical processing, biomass conversions and water oxidation-hydrogen production will be important for achieving new clean technologies. Our research work involves a novel approach to produce catalytic mechanistic properties in synthetic [...]

Polymer Nanospheres for Improved Drug Delivery of Protein Therapeutics and Viral Antigens

Castor T.P., Aphios Corporation, US

Biologically adherent polymeric microsphere carriers have been shown to be effective in the oral delivery of proteins such as insulin and DNA plasmids. These microspheres are comprised of hydrophobic copolymers that appear to have a [...]

Biologically Functionalized Nanochannels on Ferroelectric Lead Zirconium Titanate Surfaces

Ocola L.E., Pan W.C., Kuo M., Tirumala V.R., Reiss B.D., Firestone M.A., Auciello O., Argonne National Laboratory, US

We recently started a program at Argonne to exploit patterned, polarizable ferroelectric surfaces, such as lead zirconium titanate (PZT), as a means to create field-responsive inorganic-biomolecule interfaces to study and manipulate biomatter on surfaces. In [...]