optical – TechConnect Briefs

Multi-Modal Superparamagnetic Nanoprobe: Harnessing Magnetic, Nuclear, and Optical Power for Diagnostic Imaging Applications

Bumb A., Regino C.A.S., Bernardo M., Dobson P.J., Choyke P., Brechbiel M.W., National Cancer Institute, US

Accurate characterization of the first draining sentinel lymph nodes in primary tumors is a challenging task where current methods rely on nodal size as the primary yardstick for differentiating benign from malignant nodes. Other parameters [...]

Nano Crystalline Cellulose – Optical and Structural Properties by Molecular Dynamic Simulations

Kadiri Y., Simon D., Picard G., Ghozayel F., Lebreux J.-D., Ahuntsic College, CA

Structural and optical properties of Nano Crystalline Cellulose (NCC) in liquid solutions and in nematic films were investigated by large-scale molecular dynamics (MD) simulation using empirical Coulombian interaction potentials. The latter was modified by taking [...]

Nanomedicine: Engineering of a Tri-Imageable Nanoparticle

Bumb A., Brechbiel M.W., Choyke P., Fugger L., Dobson P.J., National Cancer Instiute and University of Oxford, UK

We have created a potential targeted drug delivery platform with three imaging reporters by coupling the magnetic properties of USPIOs with near infrared fluorescence of Cy5.5 and gamma emissions of Indium-111 that is chelated to [...]

Porous filter with spatially graded response

Krause K.M., Hawkeye M., Brett M., University of Alberta, CA

Glancing Angle Deposition (GLAD) has become a common technique for producing thin porous films with various structural features. In the current work, we have further modified GLAD in order to create porous structures that have [...]

A Novel Optical Waveguide Based Accelerometer

Chen F., Salcic Z., Wang J., The University of Auckland, NZ

A novel accelerometer proposed in this paper utilizes desired advantages which waveguide structure has as its sensor, such as high sensitivity due to photoelastic effect and wide spectral response range. It extends previous research by [...]

Device Characterization at the Wafer Level via Optical Actuation and Detection

Hedley J., Burdess J.S., Harris A.J., Gallacher B.J., Newcastle University, UK

This paper investigates the technique of optical actuation of MEMS. It is shown that a device can be driven into all of its vibrational modes simply and non-destructively by a laser pulse, making this an [...]

Optical Detection of Integrin AvB3 Using a Nanostructured Lipid Bilayer Membrane Biosensor

Worsfold O., Nishiya T., Fujirebio Inc., JP

An ultra-sensitive optical bionanosensor platform for integrin avb3 loaded human umbilical vein endothelial cells (HUVECs) was fabricated. The bionanosensor design involved the incorporation of an RGD (arginine-glycineaspartate) containing peptide conjugated BODIPY lipid soluble dye (donor) [...]

Micromirror Array Design and Simulation

Huja M., Husak M., Czech Technical University in Prague, CS

The main objective of the research described is to design optimal principle of micromirror array and its manufacturing technology with maximum penentration of the reflected/non-reflected part of micromirror array using standard, easily available and cheap [...]

Computer Simulation from Electron Beam Lithography to Optical Lithography

Cui Z., Rutherford Appleton Laboratory, UK

Simulation of electron beam lithography and optical lithography has been combined to investigate the influence of a distorted photomask feature on final photoresist image. Unlike the previous optical lithography simulation which was based on ideal [...]

Design and Modelling of Optical Microsystems – An Approach to a User-Friendly System Integration Technique

Wächter C., Schreiber P., Karthe W., Elbers J-P, Glingener C., Voges E., Krabe D., Dümcke R., Reichl H., Hagner G., Schröter S., Bartelt H., Stock E.A., Bauer G., Schäfer W., Sickinger H., Schwider J., Fraunhofer-Institut fur Angewandte Optikund Feinmechanik, DE

Optical microsystems usually are of a hybrid nature. They consist of optical components. i.e.micro-optical and or integrated-optical ones, and additionally they include at least mechanical and packaging components. Therefore, a complete design process has to [...]