non-viral vector – TechConnect Briefs

Synthesis and evaluation of T85-LPEI copolymers for pDNA delivery

Wang M.X., Carolinas Medical Center, US

In this study, a series of low molecular weight PEI (LPEI) modified with Tween 85 were prepared by varying feed ratio and PEI size (Mw: 0.8k, 1.2k and 2.0k Da) for gene delivery. The Mws [...]

Layer-by-Layer Deposition of Cationic Polymers on Gold Nanoparticle for Non-viral Gene Delivery System

Saengkrit N., National Nanotechnology Center (NANOTEC), TH

In this study, gold nanoparticles displayed spherical shapes with an average size of 12 nm were synthesized. The nano-carriers for gene delivery were subsequently developed based on DNA adsorption on the gold/cationic polymer-scaffold. The multilayer [...]