MRI/PET – TechConnect Briefs

Bimolecules in multimodal and multifunctional bioimaging database: potentials and applications

Sharma A., Sharma R., Sharma A., Sharma R., Innovations and Solutions Inc., US

Oligonucleotides are biomarkers in gene expression imaging and proteins for imaging proteomics based on these end product molecules as visible by MRI and PET to give structural and metabolic information in diseased tissue. We compiled [...]

Newer Methods of Nanoparticle Synthesis: Nitroimidazole properties with Nanometal oxides in Polymer Cages

Khan R.A., Sharma R., Florida State University, IN

Nitroimidazoles are radiosensitizers and hypoxia detecting chemosensitizers. Intially nitroimidazoles were single dose antibiotic drugs. Recently, nitroimidazole derivatives have emerged as multifunctional “drug-biomarker monitors” chemical compounds with importance in treatment of tumors, monitoring hypoxia and safer [...]

2-Nitroimidazole as Potential Nanoprobe in Hypoxia Imaging by MRI/PET

Sharma A., Sharma R., Sharma A., Sharma R., University of North Carolina, US

2-Nitroimidazole is radiosensitizer and serves as imaging contrast agent by 19F- and 31P MR methods. Despite the success of mesonidazole and SR-4554 compounds, very little is known of its hepato-cytotoxicity if it can be potential [...]