microarrays – TechConnect Briefs

Development of a high sensitivity fluorescence immunoassay for Amyloid Beta 42 by a silicon microarray platform

Cretich M., Gagni P., Chiari M., Consiglio Nazionale delle Ricerche, IT

Alzheimer’s disease (AD) affects millions of people around the world with rising incidence as population age. Here we present the use of a label/label free silicon/silicon oxide (Si/SiO2) based microarray platform to develop a highly [...]

Diode Laser Welding of Planar Microfluidic Devices, BioMEMS, Diagnostic Chips & Microarrays

Chen J-W, Zybko J., Clements J.T., NanoSciences, Inc., US

As polymer-based microfluidic devices, lab-chips and diagnostic platforms are pushed towards increasingly smaller geometries, advances in diode laser technology now allow for cleaner and more precise assembly. Coupling the use of photolithographic methods and mask-sets [...]

Surface Modification Chemistries and their Utilization in Microarrays, Diagnostics and Drug Delivery

Lodhi M.A., Opperman G.W., Wall J.V., Anderson A.B., SurModics, Inc., US

Availability of DNA sequence data on numerous organisms has revolutionized the way biological queries are addressed today. Focus of activity has largely shifted from discovery to application. Things that were considered far-fetched only a few [...]

Amplification of Protein Adsorption on Micro/Nanostructures for Microarray Applications

Ivanova E.P., Alekseeva Y.V., Pham D.K., Filipponi L., Nicolau D.V., Swinburne University, AU

The fabrication and operation of biodevices require the accurate control of the concentration of the bioactive molecules on the surface, as well as the preservation of their bioactivity, in particular proteins that have a significant [...]