magnetophoresis – TechConnect Briefs

Computational Fluid Dynamics Models for the Rational Design of Magnetic Microseparators – In Memory of Dr. Ed Furlani

, The Ohio State University, US

In this work, we report a numerical flow-focused study of bead magnetophoresis inside a continuous-flow microchannel in order to provide a detailed analysis of bead motion and its effect on fluid flow. Different Computational Fluid [...]

Optimization of continuous-flow magnetic bioseparators through CFD numerical models

González-Fernández C., Gómez-Pastora J., Karampelas I.H., Bringas E., Ortiz I., The Ohio State University, US

Continuous flow bioseparators allow magnetic particles that are properly functionalized so that they get attached to dangerous pathogens. Specifically, the unique properties of magnetic particles enable their separation from blood, after fulfilling their role of [...]

Field-directed and Template-assisted Magnetic Nanoparticle Self-assembly

Xue X., Furlani E.P., SUNY at Buffalo, US

The interest in field-directed assembly of colloidal magnetic nanoparticles has grown steadily in recent years due to a proliferation of applications including targeted drug therapy, biomedical imaging, among others. Such self-assembly holds promise as a [...]

Numerical Analysis of Microfluidic Magnetic Bead Separation Utilizing an Integrated Array of Magnetic Elements Magnetized by a Homogenous Bias Field

Khashan S.A., Furlani E.P., United Arab Emirates University and University at Buffalo, US

Magnetic particles are finding increasing use in microfluidic and lab-on-a-chip systems especially for bioapplications where they are commonly used to label, sort and separate target biomaterials from a sample. In this presentation we analyze the [...]

Magnetic Nanoparticle Dynamics and Assembly Phenomena in External Magnetic Fields

Xue X., Furlani E.P., SUNY-Buffalo, US

The interest in magnetic nanoparticles and ferrofluids has grown substantially in recent years as their applications continue to proliferate. Current applications are diverse and include the transport of biomolecules and therapeutic drugs [1], gene transfection [...]

Particle Transport in Magnetophoretic Microsystems

Furlani E.P., University at Buffalo, US

Magnetophoretic microsystems are finding increasing use in biotechnology and biomedicine for applications such as bioseparation and immuno-assays. These microfluidic systems typically contain embedded elements that produce a magnetic field distribution within a microchannel. This applied [...]

Modeling Magnetic Transport of Nanoparticles with Application to Magnetofection

Furlani E.P., Ng K.C., University at Buffalo, US

Magnetic nanoparticles are finding increasing use in a broad range of bioapplications, primarily as carrier particles for biomaterials such as cells, proteins, antigens and DNA. The use of biofunctional magnetic particles enables selective immobilization and [...]

A Microfluidic System for Continuous Magnetophoretic Separation of Suspended Cells Using Their Native Magnetic Properties

Han K-H, Bruno Frazier A., Georgia Institute of Technology, US

This paper presents the characterization of a continuous magnetophoretic microseparator for separating white and red blood cells from whole blood by using a high gradient magnetic separation method and microfabrication technology. The magnetophoretic microseparator directly [...]