insulin – TechConnect Briefs

Portable FRET Sensing of Proteins, Hormones, and Toxins Using DNA Aptamers and Quantum Dots

Jackson G.W., Strych U., Frank E., Willson R.C., Ballerstadt R., McNichols R.J., BioTex, Inc., US

There is an urgent need to develop methods and devices that make the monitoring of any compound of interest in the public water system more reliable, more sensitive and more economical. We are developing a [...]

Chitosan as mucoadhesive agent to enhance absorption of therapeutic proteins encapsulated into solid lipid nanoparticles

Teixeira J., Júlio A., Castro C., Fonseca J., Martins S., Ferreira D., Sarmento B., University of Porto, PT

The aim of this work was to develop Witepsol 85E solid lipid nanoparticles (SLN) containing insulin as biopharmaceutical, and to evaluate their potential for oral insulin administration. The new carrier was coated with chitosan in [...]

Invention of Polysaccharide-base Nanoparticles for Enhancing Drug Permeability across the Blood Brain Barrier

Gil E.S., Lowe T.L., Pennsylvania State University, US

The primary objective of this study is to evaluate novel cationic and degradable beta-cyclodextrin nanoparticles as drug delivery carriers for insulin across the bovine brain microvessel endothelial cell (BBMVEC) monolayer, an in vitro blood brain [...]