injection – TechConnect Briefs

Generation of picoliter and nanoliter drops on-demand in a microfluidic chip

Xu J., Attinger D., Columbia University, US

In this work, we introduce the novel technique of in-chip drop-on-demand, which consists in dispensing picoliter to nanoliter drops on demand directly in the liquid-filled channels of a polymer microfluidic chip. The technique involves a [...]

New sample injection methods for chip electrophoresis

Gaspar A., Piyasena M., Gomez F.A., California State University Los Angeles, US

Electrokinetic injection is commonly utilized in capillary chip electrophoresis (CE) even though mobility and matrix bias makes quantitation difficult. Hence, injection techniques that provide for both reproducible and precise injection of sample are warranted. Herein, [...]

Electrokinetic and Hydrodynamic Focusing/Switching in Microfluidics

Yang R-J, Chang C-C, Huang S-B, Lee G-B, National Cheng Kung University, TW

This paper presents an investigation on hydrodynamic/electrokinetic focusing and switching, which are crucial for microfluidic applications. The hydrodynamic/electrokinetic focusing phenomenon is first theoretically modeled by employing a potential flow theory, and this simple theoretical model [...]

Computer Simulations of Electrokinetic Mass Transport in Microfabricated Fluidic Devices

Ermakov S.V., Jacobson S.C., Ramsey J.M., Oak Ridge National Laboratory, US

A mathematical model and computer code for simulat-ing electrokinetic fluid and sample manipulations in micro-fabricated fluidic devices (microchips) are described. The model accounts for mass transport mechanisms such as electrophoretic migration, bulk fluid motion due [...]