endothelium – TechConnect Briefs

Magnetically Targeted Endothelial Cells for Prevention of Vascular Restenosis

Polyak B., Drexel University, US

The advent of percutaneous transluminal angioplasty with stent implantation and the even more recent use of drug-eluting stents have resulted in a paradigm shift in the care of obstructive vascular disease. However, deleterious sequelae of [...]

Polyethylene-oxide (PEO) linear nano-polymer directly stimulates endothelium and protects myocardium from focal ischemia-reperfusion injury via eNOS pathway in rats

Uryash A., Arias J., Wu H., Adams J.A., Mount Sinai Medical Center, US

Medical grade Nano-polymers (NP) used to enhance circulation, drug and gene delivery. Injection of Polyethylene-oxide (PEO) increase tissue perfusion and decrease mean blood pressure in animal models. Polyethylene-oxide (PEO) NP’s ultra high molecular weight (2-5 [...]