DNA detection – TechConnect Briefs

DNA detection using Laser Transmission Spectroscopy

Li F., Mahon A.R., Barnes M.A., Egan S., Feder J., Lodge D.M., Hwang C.-T., Schafer R., Ruggiero S.T., Tanner C.E., University of Notre Dame, US

Laser transmission spectroscopy (LTS) is a new quantitative and rapid technique for measuring the size, shape, and number of nanoparticles in suspension. We report on the application of LTS as a novel detection method for [...]

DNA Detection Using Metal-Fluorescence Interactions on Two-Dimensionally Assembled Gold Nanoparticles

Nakahara M., Taniguchi S., Inoue T., Hitachi Ltd., JP

We developed a novel DNA detection system using a single stranded probe oligonucleotide with a fluorophore immobilized on two-dimensionally assembled gold nanoparticles. This system enables the detection of amplified DNAs without fluorescence labeling. In the [...]

New Ferrocene-Functionalized Cationic Polythiophene For Label-Free Electrochemical DNA Detection

Harding-Lepage P., Le Floch F., Leclerc M., Ho H.-A., Harding-Lepage P., Leclerc M., Université Laval, CA

A specific polycationic polythiophene was discovered in order to identify dsDNA from ssDNA. The main properties of this new polymer are its conformational possibilities associated with photophysics modifications. This conjugated polymer is still subject to [...]

Cationic Polythiophene for Label-Free, Colorimetric and Fluorometric Detection of DNA

Ho H.-A., Leclerc M., Université Laval, CA

In order to respond to new demands and needs in modern medical diagnostics and biomedical research applications, a lot of new DNA detection approaches have been reported. However, most of these methods have the disadvantage [...]