cancer treatment – TechConnect Briefs

Efficient drug delivery for cancer treatment using amine-functional SiO2-LDH nanocomposites

Li L., Liu J., Gu W.Y., Gu Z., Gu W.Y., Gu Z., Liu J., Xu Z.P., Australian Institute for Bioengineering and Nanotechnology, AU

Target-specific delivery and sustained release of anticancer agents and siRNA has attracted considerable research interest in cancer chemotherapy. Recently, we have developed layered double hydroxide (LDH) vector to efficiently deliver drug and siRNA into the [...]

Inductive Nano Targeted Electromagnetic Therapy

Meymanat M., Zanjan University of Medical Sciences, Zanjan, Iran, IR

A Biofunctionalized conductor Nano-Particle which can be made of ferromagnetic and conductor materials, capable to attach specifically biologic targets in vivo and in vitro by using molecules for specific attachment (such as monoclonal antibody) is [...]

In Vitro Delivery of Docetaxel to Cancer Cells by Hybrid PLGA@Organosilica Nanoparticles with Redox-Sensitive Molecular Gates

Botella P., Quesada M., Vicente V., Cabrera A., Fabregat K., Instituto de Tecnologia Quimica (UPV-CSIC), ES

We have developed a novel hybrid material based in spherical PLGA nanoparticles containing hydrophobic molecules which have been covered by a thin layer (6-10 nm) of a redox-responsive amorphous organosilica shell. The outer layer incorporates [...]

Delivery of Camptothecin to Cancer Cells with Silica Nanoparticles

Botella P., Abasolo I., Muniesa C., Ruiz J., Fernández Y., Quesada M., Corma A., Schwartz Jr. S., Instituto de Tecnologia Quimica (UPV-CSIC), ES

We present a novel and robust delivery platform for camptothecin (CPT) based in silica nanoparticles (SNP) of 5-15 nm diameter that transport the drug attached by ester bond in 20-OH position. The surface of these [...]

The Role of Carbon Nanotubes in Enhancing the Effects of Chemotherapeutic Agents in Cancer Treatment

Mahmood M., University of Arkansas, US

Nanotoxicology is an important field of study that fills the knowledge gap concerning the introduction of nanomaterials into human cells, their interactions with biological systems, and the assessment of their risks to living organisms. In [...]

Optimal Design of Laser Surgery for Cancer Treatment Through Nanoshell-Mediated Hyperthermia Therapy

Feng Y., Rylander N., Bass J., Oden J.T., Diller K., The University of Texas at Austin, US

Recent development of nanoparticle technology and its application in hyperthermia therapies makes it possible to consider optimal control of the temperature field and thermal energy delivered to the tumor region with minimal destruction of surrounding [...]