cancer diagnostics – TechConnect Briefs

The OsteoAccess System – Low-Force, Controlled Angled Bone Access for Bone Biopsy and Bone Marrow Aspiration

Mulvihill M.L., Ashuckian E.D., Greaser J.K., Hartung K.M. Erdley H., Bagwell R.B., Actuated Medical Inc, US

Many medical procedures and diagnostics require penetrating hard cortical bone. For example, biopsies and aspirates taken from within bone are used to diagnose a wide range of cancer and blood diseases. Sampling locations can include [...]

Biochip-Based Test System for Cancer Diagnostics. Simultaneous Quantitation of Total and Free Forms of Prostate-Specific Antigen

Osipova T., Sokolova Z., Ryabykh T., Karaseva V., Modorsky M., Matveev V., Baryshnikov A., N.N. Blokhin Cancer Research Center, RAMS, RU

Background. Prostate-specific antigen (PSA) is the most useful marker for the early detection of prostate cancer (PCa). The use of two PSA forms – total (PSAt) and free (PSAf) makes it possible to differentiate benign [...]

Genomics and Proteomics: Information-Theoretic Analysis in Frequency Domain

Lyshevski S.E., Krueger F., Rochester Institute of Technology, US

We perform the frequency-domain analysis to examine large-scale genomic and proteomics data. This ensures qualitative and quantitative coherency.

Nanomedicine: Engineering of a Tri-Imageable Nanoparticle for Cancer Diagnostics

Bumb A., Dobson PJ., Fugger L., Choyke P., Brechbiel MW., National Cancer Institute/University of Oxford, US

We have created a potential targeted drug delivery platform with three imaging reporters by coupling the magnetic properties of USPIOs with near infrared fluorescence of Cy5.5 and gamma emissions of Indium-111 that is chelated to [...]