bioconjugation – TechConnect Briefs

Modular Nanoparticle Probes for Personalized in Vitro and in Vivo Imaging of Cancer Cell Populations

Nallathamby P.D., Cowden-Dahl K., Roeder R.K., University of Notre Dame, US

The high mortality and poor prognosis for women diagnosed with ovarian cancer is mainly due to late diagnosis. Improved detection of primary tumors and recurrence after chemotherapy is, therefore, crucial to reduce ovarian cancer mortality [...]

Hydroxylamine-O-sulfonic acid as a New Reducing Agent for the Formation of Nearly Monodisperse Gold Nanoparticles in water: Synthesis Characterisation and Bioconjugation

Rahme K., Holmes J.D., Notre Dame University (Louaize), LB

Gold nanoparticles (Au NPs), with diameters ranging between 60-150 nm, have been synthesised in water at room temperature by reducing HAuCl4.3H2O with hydroxylamine-o-sulfonic acid in the presence of sodium citrate, as stabilising agent. 15 and [...]

Electronic effects in CdSe/ZnS quantum dots conjugated to Interleukin 10 antibodies

Torchynska T.V., Casas Espinola J.L., Douda J., López de la Luz O.S., Instituto Politecnico Nacional, MX

Photoluminescence (PL) and Raman scattering spectra of none- and bio-conjugated CdSe/ZnS and CdSeTe/ZnS quantum dots (QDs) have been studied. QDs, characterized by emission at 605, 655 and 705nm, have been conjugated with anti Interleukin 10 [...]