aptamers – TechConnect Briefs

Electromechanical Detection of Pathogens with Self-Assembled Nucleic Acid Biosensors

Urmann K., Bahnemann J., Chikneyan Z., Kasmaee L.M., Hoffmann M.R., California Institute of Technology, US

Infectious diseases, primarily caused by enteric pathogens, remain a major cause of death, especially in remote locations of the developing world. Routine monitoring of pathogen contaminations is therefore crucial. We seek to apply quartz crystal [...]

Portable FRET Sensing of Proteins, Hormones, and Toxins Using DNA Aptamers and Quantum Dots

Jackson G.W., Strych U., Frank E., Willson R.C., Ballerstadt R., McNichols R.J., BioTex, Inc., US

There is an urgent need to develop methods and devices that make the monitoring of any compound of interest in the public water system more reliable, more sensitive and more economical. We are developing a [...]

Single-Walled Carbon Nanotube Network based Biosensors using Aptamers and its Characteristics

Kim D.W., Seo S.M., Park Y.J., Seoul National University, KR

We have successfully demonstrated the single-walled carbon nanotube (SWNT) network based biosensor using aptamers as the protein recognition site. The single-walled carbon nanotube network was used to improve the uniformity in I-V characteristics. Aluminum was [...]

High-sensitive Label-free Biosensors Based on Carbon Nanotube Field-effect Transistors Modified with Aptamers

Maehashi K., Katsura T., Matsumoto K., Kerman K., Takamura Y., Tamiya E., Osaka University, JP

We have fabricated label-free protein biosensors based on aptamer-modified carbon nanotube field-effect transistors (CNTFET) for detection of immunoglobulin E (IgE). Since aptamers are artificial oligonucleotides, the aptamers are smaller in size than the Debye length. [...]