amyloid fibrils – TechConnect Briefs

Nanoscale SPM Characterisation of Nacre Argonite Plates and Synthetic Human Amyloid Fibres

Grishin I., Tinker C., Allsop D., Robson A., Kolosov O.V., Lancaster University, UK

Nacre exhibits structural robustness despite the brittle nature of its constituents. A detailed understanding of its fabrication principles developed in nature can lead to new ideas in material design and synthesis. But due to this [...]

3D-RISM-KH approach for biomolecular modeling at nanoscale: Thermodynamics of fibril formation and beyond

Blinov N., Dorosh L., Wishart D., Kovalenko A., University of Alberta/National Institute for Nanotechnology, CA

As an alternative to the conventional solvation models, we propose to use the three-dimensional molecular theory of solvation (3D-RISM-KH approach) as an essential part of a multiscale approach for nanomedical applications. Based on the rigorous [...]