Automated Microfluidic Chip and System for the Synthesis of Radiopharmaceuticals on Human-Dose Scales
van Dam R.M., Elizarov A.M., Ball E., Shen C.K-F, Kolb H., Rolland J., Diener L., Williams D., Edgecombe B., Stephen T., Heath J.R., Siemens Molecular Imaging Biomarker Research, US
We present a fully-automated microfluidic system for the multi-step chemical synthesis of radiopharmaceuticals such as radiolabeled probes for positron emission tomography (PET). In earlier work, we developed a proof-of-principle PDMS microfluidic chip with a coin-shaped [...]