Vreeland W.N. – TechConnect Briefs

A New Separation Metric for the Optimization of AF4 Separations of Polydispersed Nanomaterials

Galyean A.A., Vreeland W.N., Filliben J.J., Holbrook R.D., Weinberg H.S., University of North Carolina at Chapel Hill, US

The development of standardized and optimized methods to monitor the behavior of engineered nanomaterials (ENMs) in complex environments is considered a critical component in ENM risk assessment. Robust, rigorously optimized methods are currently lacking, in [...]

A New Separation Metric for the Optimization of AF4 Separations of Polydispersed Nanomaterials

Galyean A.A., Vreeland W.N., Filliben J.J., Holbrook R.D., Weinberg H.S., University of North Carolina at Chapel Hill, US

The development of standardized and optimized methods to monitor the behavior of engineered nanomaterials (ENMs) in complex environments is considered a critical component in ENM risk assessment. Robust, rigorously optimized methods are currently lacking, in [...]

Microfluidic Synthesis of Nano-Liposomal Anesthetics

Hood R.R., Kendall E.L., Vreeland W.N., Junqueira M., Finkel J.C., DeVoe D.L., University of Maryland, US

Sophisticated analytical technologies are available enabling the direct correlation of physicochemical structure to overall function and formulation attributes through generation of spatially resolved information. This presentation will cover two case studies where advanced, surface sensitive [...]

Controlled Encapsulation of a Hydrophilic Drug Simulant in Nano-Liposomes using Continuous Flow Microfluidics

Jahn A., Reiner J.E., Vreeland W.N., DeVoe D.L., Locascio L.E., Gaitan M., National Institute of Standards and Technology, US

A new method to tailor the size and size distribution of nanometer scale liposomes in a continuous-flow microfluidic design is presented. Encapsulation of a model drug into the liposomes is analyzed with Fluorescence Fluctuation Spectroscopy [...]