Uchegbu I.F. – TechConnect Briefs

Fast gelation of self-assembling peptide nanofibres triggered by electromagnetic radiation heating

Mazza M., Gaisford S., McCharty D., Uchegbu I.F., The School of Pharmacy, University of London, UK

We report a method for the preparation of peptide nanofibre gels prepared by a rapid heating/cooling cycle employing electromagnetic radiation heating. An amphiphilic peptide having a C16 chain attached via an esteric link was used [...]

Modified glycol chitosan nanocarriers carry hydrophobic materials into tumours

Raza A., de-la Fuente M., Uchegbu I.F., Schätzlein A., Nuclear Medicines Oncology & Radiotherapy Institute, PK

Etoposide is a potent anticancer drug commonly used in a variety of malignancies. High protein binding, requirement of fairly high doses of drugs to achieve sustained plasma levels and hypersensitivty issues are related to its [...]