Reduction-sensitive hyaluronic acid nanoparticles for targeted intracellular deliery of doxorubicin
Disulfide-containing HA dodecyl conjugates (HA-SS-DDTs) were synthesized using the facile thiol-exchange reaction as the carrier for intracellular delivery of doxorubicin (DOX). Owing to its amphiphilicity, HA-SS-DDT could form self-assembled nanoparticles in an aqueous condition. The [...]