Prakash S. – TechConnect Briefs

PEG Incorporated Polymeric Microcapsules for Intramyocardial Delivery of Stem Cells Genetically Modified by Baculovirus

Paul A., Khan A.A., Abbasi S., Shum-Tim D., Prakash S., McGill University, CA

The ability of mesenchymal stem cells to self-renew and differentiate into specialized cell lineages makes them promising tools for regenerative medicine. Local injection and use of scaffolds had been employed earlier to deliver these cells; [...]

Nanoparticles co-encapsulating hVEGF and hAng-1 can induce mitotic and antiapoptotic effect on vascular endothelial cells

Khan A.A., Paul A., Abbasi S., Prakash S., McGill University, CA

This study demonstrates the combined effect of the angiogenic proteins, hVEGF and hAng-1, coencapsulated in human serum albumin (HSA) nanoparticles (NPs), towards human umbilical vein endothelial cells (HUVECs) and an evaluation of the potential application [...]

siRNA Delivery Using Biodegradable Nanoparticles for Breast Cancer Therapy

Abbasi S., Arghya P., Afshan K., Prakash S., McGill University, CA

Polyethylenimine (PEI)-coated human serum albumin (HSA) nanoparticles form suitable biocompatible carriers for therapeutic molecules. Small interfering RNA (siRNA) molecules have suggested great promise as a future therapy for breast cancer. In order to overcome the [...]