Moscatelli D. – TechConnect Briefs

Influence of His-195 on the nitrogenase FeMo-cofactor activity

Cavallotti C., Moscatelli D., Carrà S., Politecnico di Milano, IT

Mo-nitrogenase is the enzyme responsible for the conversion of atmospheric nitrogen to ammonia. Its active site is the iron-molibdenum cofactor, FeMo-co, which is composed by two incomplete cubes, Fe4S3 and MoFe3S3, connected through three bridging [...]

A Kinetic Study of the MOCVD of GaN

Moscatelli D., Cavallotti C., Politecnico di Milano, IT

Quantum chemistry investigations have been performed to study the gas phase chemistry active during the MOVPE of GaN when Ga(CH3)3 and NH3, diluted in a H2 carrier gas, are used as precursors. Optimized molecular geometries, [...]

Molecular Dynamic investigation of the interaction of supported affinity ligands with Monoclonal Antibodies

Zamolo L., Busini V., Moiani D., Moscatelli D., Cavallotti C., Politecnico di Milano, IT

Monoclonal antibodies are gaining an increasing importance in diagnostic and therapeutic treatment of grave diseases such as immunodeficiency, Alzheimer’s syndrome and cancer. The production of these pharmaceuticals and especially the purification step, however, are still [...]

Influence of His-195 on the nitrogenase FeMo-cofactor activity

Cavallotti C., Moscatelli D., Carrà S., Politecnico di Milano, IT

Mo-nitrogenase is the enzyme responsible for the conversion of atmospheric nitrogen to ammonia. Its active site is the iron-molibdenum cofactor, FeMo-co, which is composed by two incomplete cubes, Fe4S3 and MoFe3S3, connected through three bridging [...]