Li H.X. – TechConnect Briefs

Label Free Colorimetric Detection of Single Nucleotide Polymorphisms in Pcr Amplified Genomic DNA

Li H.X., Rothberg L.J., University of Rochester, US

Analysis of DNA is increasingly important in clinical diagnosis, pathology and genetics1, 2. Single nucleotide polymorphisms (SNPs) in genomic DNA are known to be responsible for a number of hereditary conditions3 and cancers4. Nearly all [...]

Rapid DNA Sequence Identification based on Electrostatic Interactions with Unmodified Gold Nanoparticles

Li H.X., Rothberg L.J., University of Rochester, US

Sequence-specific detection of DNA play more and more important role in clinical diagnosis and molecular biology research. Most assays identify specific sequence through hybridization of an immobilized probe to the target analyte after the latter [...]