Targeted Aptamer-Nanoparticles to Diminish Drug Resistance of Cancer Cells in vitro Study
Basto P., Alexis F., Levy-Nissenbaum E., Langer R., Farokzhad O., Massachusetts Institute of Technology, US
Using prostate cancer as a model, we report the drug release of pacitaxel and doxorubicin from aptamer-poly (D,L lactic co glycolic acid)-poly(ethylene glycol) (PLGA-PEG) nanoparticles used to target prostate-specific membrane antigen (PSMA), a well characterized [...]