Ges I.A. – TechConnect Briefs

Amperometric glucose sensor for real time extracellular glucose monitoring in microfluidic device

Ges I.A., Baudenbacher F.J., Vanderbilt University, US

Glucose and lactate are the most important metabolites which characterize physiological state and the metabolic activity of living cells. Consequently, development of a stable glucose biosensor is an interesting and important research topic for medicine [...]

Investigation of pH behavior of single myocyte cells in picoliter microfluidic device

Ges I.A., Baudenbacher F.J., Vanderbilt University, US

The possibility to investigate single cell metabolic activity in real time in sub-nanoliter volume could expand our knowledge of cellular physiological processes. Extracellular pH is a critical parameter for many cellular processes and extracellular acidification [...]

Integrated microfluidic device to monitor the cells acidification rate in nanoliter volumes using microfabricated iridium oxide electrodes

Ges I.A., Ivanov B.L., Baudenbacher F.J., Vanderbilt University, US

In our work we describe a new approach to measure pH differences in microfluidic devices and demonstrated acidification rate measurements in on-chip cell culture systems with nanoliter wells. We used two miniaturized identical iridium oxide [...]