Chitosan as mucoadhesive agent to enhance absorption of therapeutic proteins encapsulated into solid lipid nanoparticles
Teixeira J., Júlio A., Castro C., Fonseca J., Martins S., Ferreira D., Sarmento B., University of Porto, PT
The aim of this work was to develop Witepsol 85E solid lipid nanoparticles (SLN) containing insulin as biopharmaceutical, and to evaluate their potential for oral insulin administration. The new carrier was coated with chitosan in [...]