Esquivel D. – TechConnect Briefs

Molar variation of water: alkoxy in the preparation of SiO2-DA materials and its effect on dopamine release from an implantable reservoir in the brain

Lopez T., Esquivel D., Garcia E., National Institute of Neurology and Neurosurgery, MX

In the present work we report the dopamine (DA) molecules stabilization in the network of nanostructured silica materials with the objective of using these as reservoirs of DA release in the brain. For this purpose [...]

Spectroscopical and Structural Studies of Sol-gel Reservoirs used as Implants in the Delivery of Dopamine to the Central Nervous System

Lopez T., Esquivel D., Ascencio J., Odriozola J.A., Gonzalez R.D., Tulane University, US

The stabilization of dopamine used in the treatment of Parkinsons is a pressing problem. When dopamine is applied systemically. destabilization may occur following penetration through the blood brain barrier (BBB). In order to circumvent this [...]