Development of Tumor Targeting Magnetic Nanoparticles for Cancer Therapy
Ivkov R., DeNardo G.L., DeNardo S.J., Miers L.A., Natarajan A., Foreman A.R., Gruettner C., Adamson G.N., DeNardo G.L., DeNardo S.J., Triton BioSystems, Inc., US
111In-ChL6 MAb-linked iron oxide nanoparticles (bioprobes) pharmacokinetics, tumor uptake and the therapeutic effect of inductively heating these bioprobes by an externally applied AMF were studied in athymic mice bearing human breast cancer HBT3477 xenografts. Bioprobe [...]