Cluster assembled nanostructured TiO2 film mediates efficient and safe retroviral gene transduction in primary adult human melanocytes for ex-vivo gene therapy
Carbone R., Marangi I., Zanardi A., Lanfrancone L., Minucci S., Pelicci P.G., Giorgetti L., Clerici E., Bongiorno G., Piseri P., Milani P., European Institute of Oncology, IT
Primary human melanocytes represent the precursor cells to melanoma and also specific targets of inherited and acquired pigmentation disorders (1,3). The possibility to genetically manipulate these cells for biological studies or therapy has not been [...]