Cerize N.N.P. – TechConnect Briefs

Skin permeation of hydrophobic drugs loaded into polymeric nanoparticles

Feitosa V.A., Balogh T.S., Guimarães K.L., Zanin M.H.A., Oliveira A.M., Cerize N.N.P., Institute for Technological Research – IPT, BR

Polymeric nanoparticles have been employed for topical pharmaceutical applications due to its capacity to carry drugs across the skin. Biocompatible polymers are extensively applied as coating nanoparticles allowing them present controlled physical and chemical characteristics. [...]

Electrospun nanofibers for Sustained Delivery of Cetylpyridinium Chloride for Buccal Topical Application

Zanin M.H.A., Santos V.A., Oliveira A.M., Cerize N.N.P., Borsatti M.A., Institute for Technological Research of the State of São Paulo - IPT, BR

The aim of this study was to prepare electrospun polymeric nanofiber mat composed of polyvinylpyrrolidone (PVP-Kollidon® 90F), ammonio methacrylate copolymer type B (PMMA-Eudragit® RS100) and cetylpyridinium chloride (CPC), 10:10:1 (wt/wt%) and its characterization for buccal [...]

Rifampicin nanosuspension production using microfluidic device

Schianti J.N., Cerize N.N.P., Oliveira A.M., Derenzo S., Gongora-Rubio M.R., Polytechnic School - University of São Paulo, BR

In this work the results of a study of Rifampicin nanoprecipitation through antisolvent technique are presented, using microfluidic devices. Rifampicin is commonly used in Tuberculosis treatment and presents variability in bioavailability. The particle size and [...]