Bergstrom D.E. – TechConnect Briefs

Assembly of Nanoscale Scaffolds from Peptide Nucleic Acids (PNA)

Husk Jr. T., Bergstrom D.E., Purdue University, US

Deoxyribonucleic acid or DNA has been demonstrated to be a useful scaffold for self-assembling nanomaterials. Peptide nucleic acids, or PNA, which retains the nucleic acid bases adenine, cytosine, guanine, and thymine on a pseudo-peptide backbone [...]

DNA-Associated Single-walled Carbon Nanotubes as a Platform for Drug Delivery

Dolash B.D., Lahiji R.R., Zemlyanov D.Y., Reifenberger R., Bergstrom D.E., Purdue University, US

DNA-associated single walled carbon nanotubes(DNA:SWCNTs) have shown potential in drug delivery with the ability to translocate across the cell membrane carrying various biomolecules. Our laboratory has completed a series of experiments to show the sonication [...]

Development of Peptide Nucleic Acid Assemblies for Application in Drug Delivery and Molecular Sensing

Butler F.N., Elibol O., Hines B.D., Reddy Jr. B., Bashir R., Bergstrom D.E., Purdue University, US

We are exploring peptide nucleic acid (PNA) assemblies as interesting scaffolds for the fabrication of nanomaterials relevant to the diagnosis and treatment of disease. The first assembly is a PNA/LNA (locked nucleic acid) duplex employed [...]