University of Southern Maine – TechConnect Briefs

Cytotoxicity and genotoxicity of silver nanomaterials

Uyguy B., Mason M.D., Ng A-K., University of Southern Maine, US

Summary We have investigated the cytotoxic effect of dialyzed silver nanoparticles (Ag NPs), PEGylated Ag NPs and silver nanorods on human cultured cells. The cytotoxicity of 24 h treatment with Ag NPs at 0.25, 0.5, [...]

Cell-based Assays for Cytotoxic and Pro-inflammatory Effects of Gold Nanoparticles

Knight T., Wise S.S., Wise_Sr. J.P., Mason M.D., Wise_Sr. J.P., Ng A-K., University of Southern Maine, US

This study aims at developing cell-based assays to assess the potential cytotoxic and proinflammatory effects of nanomaterials, using 15 nm gold nanoparticles as a model. In a MTT cytotoxicity assay, significant cytotoxicity was found in [...]