Kyoto Institute of Technology – TechConnect Briefs

Mutations of cypovirus polyhedrin and applications of polyhedra to protein nanocontainers

Ohtsuka Y., Nakai D., Coulibaly F., Chiu E., Metcalf P., Mori H., Kyoto Institute of Technology, JP

Cypoviruses, a member of the family Reoviridae, are one group of insect virus that produce micrometer-sized protein crystals called cytoplasmic polyhedra. Many virus particles are occluded in polyhedra to protect them against extracellular environment. Recently [...]

Application of insect virus polyhedra to protein nanocontainers

Mori H., Ijiri H., Kotani E., Kyoto Institute of Technology, JP

Certain insect viruses encode a protein called polyhedrin that forms polyhedric crystals, or polyhedra, within an infected cell. The virus particles, or virions, are protected within these polyhedra and can remain infectious for years outside [...]

Immobilization of bioactive growth factors into cubic proteinous microcrystals (cypovirus polyhedra) and control of cell proliferation and differentiation

Mori H., Kyoto Institute of Technology, JP

Certain insect viruses produce stable infectious microcrystals called polyhedra which function to protect the virus after the death of infected larvae. Polyhedra form within infected cells and contain numerous virus particles embedded in a crystalline [...]