Targeting tumor associated macrophages using clodronate-loaded PLGA nanoparticles
Sharma G., Karmali P., Ramirez M., Xie Hui, Ruoslahti E., Smith J., Burnham Institute for Medical Research, US
There is increasing evidence now that tumor associated macrophages (TAMs) play a key role in tumor growth and metastasis by promoting tumor angiogenesis. Macrophages are also prominent in tumor tissues, comprising up to 80% of [...]