Brigham and Women’s Hospital, Harvard Medical School

Differential Cytotoxicity of Metal Oxide Nanoparticles

Chen J., Zhu J., Cho H.-H., Cui K., Li F., Zhou X., Rogers J.T., Wong S.T.C., Huang X., Brigham and Women's Hospital, Harvard Medical School, US

There are growing concerns among the general public and regulators about their potential health hazard. To determine the potentially toxic responses of CNS due to exposure of metal oxide nanoparticles, human SH-SY5Y neuroblastoma and H4 [...]

Targeted Nanoparticle-Polypeptide Conjugates for Breast Cancer Treatment

Alexis F., Basto P., Radovic-Moreno A., Langer R., Farokhzad O.C., Brigham and Women's Hospital, Harvard Medical School, US

We have developed a polymeric targeted nanoparticle-polypeptide conjugates that shows cell binding speficity and stealth properties. The targeted naoparticles binds and are taken up efficiently by Her2 expressing breast cancer cells. These nanoparticles represent a [...]