US – Page 52 – TechConnect Briefs

nano Droplet Array Plates (nDAPs): 3D Cell Culture in Anchored Hydrogel Droplets Compatible with Conventional Microplates

Xu Q.F., Chen X., Lyons A.M., ARL Designs LLC, US

University researchers as well as large pharmaceutical companies need improved technologies for discovering new drugs. Current drug-discovery approaches are highly inefficient, as

Field-directed Self-assembly of Multifunctional Magnetic-Plasmonic Core-shell Nanoparticles with Applications to Photonics

Xue X., Liu K., Wang J., Furlani E.P., University at Buffalo (SUNY), US

Interest in the manipulation and self-assembly of magnetic nanoparticles has grown in recent years due to advances in particle synthesis and functionalization, which have led to a proliferation of applications that include the biomolecular transport, [...]

Microfluidic platform for studies of self-organizing processes in a bacterial cell

Yang D., Jennings A., Männik J., University of Tennessee, US

Cells maintain their structure and reproduce through numerous self-organizing processes. The common approach to understand how cellular organization is maintained is to perturb this organization and then observe a response from the cell. Essentially all [...]

Fabrication of Conductive Nanoporous Membranes using Self-Assembling Block for Electrically Controlled Diffusive Flow

Ozalp E.I., Kim S., Sundar V., Zhu J.-G., Weldon J.A., Carnegie Mellon University, US

Nanoporous membranes have been recognized as promising candidates for drug delivery applications due to their small pore size and high surface-to-volume ratio1. The ultimate goal of smart drug delivery systems is to release a specific [...]

Acne Treatment based on Selective Photothermolysis of Sebaceous Follicles with Topically Delivered Gold Plasmonic Particles

Paithankar D., Meyer T., Blomgren R., Faupel L., Lando A., Anderson R., Sebacia, Inc., US

A laser treatment for acne, one of the most common dermatologic conditions, with 150 nm diameter plasmonic resonant particles tuned to absorb near infrared light has been developed. Acne lesions originate from sebaceous follicles; the [...]

Numerical modeling of the effect of field configurations on the magnetic nanoparticle delivery

Ghantasala M.K., Ikonomov P., Rajh T., David A., Western Michigan University, US

Numerical modeling of the effect of field configurations on the magnetic nanoparticle delivery Muralidhar K. Ghantasala1, Pavel Ikonomov2, Tijana Rajh#, and Allen David* 1Department of Mechanical and Aerospace Engineering,2 Department of Engineering Design, Manufacturing, and [...]

Plasmonic Nanocages as Photothermal Transducers for Nanobubble Cancer Therapy

Karampelas I.H., Liu K., Furlani E.P., University at Buffalo (SUNY), US

The ability to generate and control thermal energy with nanoscale resolution is finding increasing use in a variety of applications spanning the fields of nanoparticle synthesis, nanofabrication, bio-imaging and medical therapy [1, 2]. One of [...]

Nanobiomimetic Memristor/memcapacitors’ Function as a Voltage Sensor for Direct and Reagent-free Detection of sub pg Lipopolysaccharide (LPS) in Milks for Children

Duh S-H, Thornton J., Kissinger P.T., Chen E.T., advanced biomimetic sensnors, inc, US

Lipopolysaccharide (LPS) is a common endotoxin from E. Coli bacteria, and is the major source causing infection diseases over 20 million people worldwide. Lack of sensitivity and high imprecision from common commercial test methods are [...]

Nanobiomimetic Memristor/Memcapacitor Devices Used for Direct and Reagent-less Detection of Sub pM Acetyl Coenzyme A in Milks

Duh S-H, Thornton J., Kissinger P.T., Chen E.T., advanced biomimetic sensnors, inc, US

Acetyl co-enzyme A (AcCoA) is a leading substrate in a large variety of enzyme-catalyzed reactions, such as for choline acetyltransferase and acetylcholinesterase. They are critical to energy production, metabolism, memory, cell proliferation and early childhood [...]

High efficiency capture of multiple bacterial species by microfluidic dielectrophoresis filter

Simon S., Weber M., Fluid-Screen, Inc., US

Fluid-Screen, Inc. presents a bacterial concentration and filtration method based on dielectrophoresis (DEP). DEP has been known to induce particle motion since the 1960’s. However, yields and reproducibility have consistently been low in practice, reducing [...]