US – Page 274 – TechConnect Briefs

Strategies for enhanced brain tumor accumulation of magnetic nanoparticles for potential drug delivery

Chertok B., David A.E., Yang V.C., University of Michigan, US

The purpose of this study was to elucidate strategies to enhance magnetically mediated accumulation of iron-oxide-based nanoparticles in brain tumors for potential localized delivery of chemotherapeutic agents. In particular, we evaluated administration of the nanoparticles [...]

Gold Nano-Probes as Targeted CT Contrast Agents for In-vivo cancer Imaging

Popovtzer A., Popovtzer R., Agrawal A., Shlomi M., Popovtzer A., Popovtzer R., Balter J., Carey T.E., Kopelman R., University of Michigan, US

This research describes a new class of immuno-targeted and cancer specific CT contrast agents, which enable CT imaging of cancer at cellular and molecular resolution. The method is based on the development of gold nano-probes [...]

Nanomedicine: Engineering of a Tri-Imageable Nanoparticle for Cancer Diagnostics

Bumb A., Dobson PJ., Fugger L., Choyke P., Brechbiel MW., National Cancer Institute/University of Oxford, US

We have created a potential targeted drug delivery platform with three imaging reporters by coupling the magnetic properties of USPIOs with near infrared fluorescence of Cy5.5 and gamma emissions of Indium-111 that is chelated to [...]

Why Does One Nano Lab Cost More Than Another?

Wilson W., Gregg A., Wilson Architects, US

Construction costs of nano labs reflect the differential between the required performance criteria and the in situ conditions. Nano retrofits in existing buildings range from $300 to $1000 NSF, depending on the isolation required. New [...]

Partnering in Nanotechnology Ventures: Critical Decision Factors

Woolley J.L., Santa Clara University, US

Business executives are often faced with the decision of whether to optimize the firm’s performance by partnering with another company or exploring growth alone. Although nanotechnology firms are no exception, the high level of tacit [...]

Nanotechnology in Pharmaceutical Education In USA

Pathak Y.V., Koomer A., Sullivan University College of Pharmacy, US

Nanotechnology is on its way to make a big impact in Biotech, Pharmaceutical and Medical diagnostics sciences. A dynamic collaboration is observed within the Researchers, Government, Pharmaceutical - Biomedical companies and educational institutions all over [...]

Designing the new engineer and scientist

Wauters J., De Wachter J., Flanders Investment and Trade - Consulate General of Belgium, US

Bio-nano science and technology is reaching a high level of technical expertise and knowledge. It opens up completely new ways of design, production and manufacturing. It has the capacity to impact the whole industry, the [...]

Leveraging the Nation’s Nanotechnology Research Centers: True interdisciplinary buildings foster a seamless transition from lab bench to consumer

Soueid A., Adams G., Schaeffer M., Riojas S., HDR Architecture, Inc., US

Successfully fostering emerging technologies requires diligence in continually assessing and evolving best practices resulting in process improvements. While nanotechnology is in many ways still considered an emerging field, it is rapidly becoming the corner stone [...]

The importance of R&D alliances to sustain a nano-biotechnology ecosystem

Wauters J., Flanders Investment and Trade - Consulate General of Belgium, US

The breakthroughs in nanoelectronics, nanotechnology and biotechnology are resulting in a growing convergence of nano with bio, as they both ‘work’ at the nanoscale. Think e.g. of nanotherapeutics, where nanoparticles, loaded with drugs, can be [...]

Maintaining Clean Surfaces in Cryogenic Measurement Environments

Lindemuth J., Lake Shore Cryogenics, US

Surfaces of nanoscale materials of all types must be kept clean to properly characterize their behavior. Materials that are characterized at cryogenic temperatures and in vacuum present additional challenges to maintaining clean surfaces. Any residual [...]