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Country: US
A Co-Culture Model for Nanotoxicity and Tissue Engineering Studies
Wang Y.-H., Jandhyam S., Dukhande V.V., Gao W.J., Gu H.-Y., Lai J.C.K., Lai M.B., Leung S.W., Lai J.C.K., Lai M.B., Idaho State University College of Pharmacy & Biomedical Research Institute, US
Cell model systems in vitro play vital roles in recent advances in toxicological and tissue engineering research. They are particularly versatile in facilitating signaling and related mechanistic studies. Although the 3-D cell models better simulate [...]
In Vitro Diagnosis and Analysis of the Potential Effects of Carbon Nanotube Exposure on the Human Respiratory System
Recent discoveries of various forms of carbon nanostructure have stimulated researches on their applications and hold promise for applications in medicine and many other related engineering areas. While carbon nanotubes (CNT’s) are already being produced [...]
Monte Carlo Multi-Criteria Risk Analysis of Single Wall Carbon Nanotube Production Processes Under Uncertain Manufacturing Costs, Occupational Health Risks, and Regulatory Standards
Considerable uncertainty exists regarding full-scale manufacturing costs, occupational risks, and probable future regulatory standards for various single wall carbon nanotube (SWNT) manufacturing processes. Monte Carlo models have been developed to investigate these implications and compare [...]
Nanomaterials down the drain: perception and reality
The fate of nanoparticles in commercial products at the end of product life is not entirely clear. This uncertainty, coupled with the unknowns regarding the potential for risks to human health and the environment, could [...]
Development and Application of an Exposure-based Framework for Assessing Nanomaterial Safety
Although the Project on Emerging Nanotechnologies estimates that there are already over 500 nanotechnology-based consumer products on the market, few published data are available to support thorough nanomaterial safety assessments. To address questions of product [...]
Differential Cytotoxicity of Metallic Oxide Nanoparticles in Mammalian Cells
Lai J.C.K., Lai M.B., Jandhyam S., Dukhande V.V., Bhushan A., Daniels C.K., Leung S.W., Lai J.C.K., Lai M.B., Idaho State University, US
Nanomaterials have been increasingly used in industrial applications (e.g., drug delivery, additives to drugs and cosmetics). Because of their wide use, occupational exposure to nanomaterials and nanoparticles may pose as health risks. Recent studies have [...]
Silicon Dioxide Nanoparticles Exert Dissimilar Cytotoxic Effects on Mammalian Cell Types
Jandhyam S., Lai J.C.K., Lai M.B., Dukhande V.V., Bhushan A., Daniels C.K., Leung S.W., Lai J.C.K., Lai M.B., Idaho State University, US
Applications of nanomaterials (e.g., silicon dioxide (SiO2) nanoparticles) are ubiquitous. Thus, environmental and occupational exposure to these nanoparticles could pose potential health risk. SiO2 microparticles are toxic in animals in vivo and SiO2 nanoparticles are [...]
Cytotoxic Effects of Short Multi-wall Carbon Nanotubes
The applications of carbon nanotubes (CNTs), a novel and important class of nanomaterials, can change paradigms of various research areas. Although biomedical applications of CNTs are increasing, their putative cytotoxicity has not been substantially addressed. [...]
Nanofiltration of Electrolyte Solutions by Sub-2nm Carbon Nanotube Membranes
Fornasiero F., Park H.G., Holt J.K., Stadermann M., Kim S., In J.B., Grigoropoulos C.P., Noy A., Bakajin O., Lawrence Livermore National Laboratory, US
Both MD simulations and experimental studies have shown that liquid and gas flow through carbon nanotubes with nanometer size diameter is exceptionally fast. For applications in separation technology, selectivity is required together with fast flow. [...]